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Structural Basis for Inhibition of Histamine N-Methyltransferase by Diverse Drugs
In mammals, histamine action is terminated through metabolic inactivation by histamine N-methyltransferase (HNMT) and diamine oxidase. In addition to three well-studied pharmacological functions, smooth muscle contraction, increased vascular permeability, and stimulation of gastric acid secretion, h...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4021489/ https://ncbi.nlm.nih.gov/pubmed/16168438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2005.08.040 |
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