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Mutant B-RAF Regulates a Rac-dependent Cadherin Switch in Melanoma

The ability of cells to invade into the dermis is a critical event in the development of cutaneous melanoma and ultimately an indicator of poor prognosis. However, the molecular events surrounding the acquisition of this invasive phenotype remain incompletely understood. Mutations in B-RAF are frequ...

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Detalhes bibliográficos
Main Authors: Elizabeth, Monaghan-Benson, Burridge, Keith
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021488/
https://ncbi.nlm.nih.gov/pubmed/23208503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.492
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