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CPEB1 promotes differentiation and suppresses EMT in mammary epithelial cells

Downregulation of CPEB1, a sequence-specific RNA-binding protein, in a mouse mammary epithelial cell line (CID-9) causes epithelial-to-mesenchymal transition (EMT), based on several criteria. First, CPEB1 knockdown decreases protein levels of E-cadherin and β-catenin but increases those of vimentin...

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Détails bibliographiques
Auteurs principaux: Grudzien-Nogalska, Ewa, Reed, Brent C., Rhoads, Robert E.
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021476/
https://ncbi.nlm.nih.gov/pubmed/24634508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.144956
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