An in vivo test of the hypothesis that glucose in myeloid cells stimulates inflammation and atherosclerosis

Inflammatory activation of myeloid cells is accompanied by increased glycolysis, which is required for the surge in cytokine production. Although in vitro studies suggest that increased macrophage glucose metabolism is sufficient for cytokine induction, the pro-inflammatory effects of increased myel...

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Main Authors: Nishizawa, Tomohiro, Kanter, Jenny E., Kramer, Farah, Barnhart, Shelley, Shen, Xia, Vivekanandan-Giri, Anuradha, Wall, Valerie Z., Kowitz, Jason, Devaraj, Sridevi, O’Brien, Kevin D., Pennathur, Subramaniam, Tang, Jingjing, Miyaoka, Robert S., Raines, Elaine W., Bornfeldt, Karin E.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021396/
https://ncbi.nlm.nih.gov/pubmed/24726364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.03.028
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