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Ubiquitin ligase A20 regulates p53 protein in human colon epithelial cells

BACKGROUND: Intestinal polyps may further develop into colon cancer; the pathogenesis is not clear. The p53 gene is an important anti-cancer gene in the body, which is suppressed in cancer. The ubiquitin E3 ligase A20 (A20) plays a role in regulating the activities of epithelial cells. This study wa...

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Autors principals: Liu, Jing, Yang, Shaobo, Wang, Zhiqiang, Chen, Xiao, Zhang, Ziqi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021182/
https://ncbi.nlm.nih.gov/pubmed/24099634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-20-74
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