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HIFs Enhance the Transcriptional Activation and Splicing of Adrenomedullin

Adrenomedullin (ADM) is important for tumor angiogenesis, tumor cell growth and survival. Under normoxic conditions, the ADM gene was found to produce two alternative transcripts, a fully-spliced transcript that produces AM and PAMP peptides and a intron-3-retaining transcript that produces a less f...

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Detalhes bibliográficos
Main Authors: Sena, Johnny A., Wang, Liyi, Pawlus, Matthew R., Hu, Cheng-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020993/
https://ncbi.nlm.nih.gov/pubmed/24523299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0607
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