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STAT3 or USF2 Contributes to HIF Target Gene Specificity
The HIF1- and HIF2-mediated transcriptional responses play critical roles in solid tumor progression. Despite significant similarities, including their binding to promoters of both HIF1 and HIF2 target genes, HIF1 and HIF2 proteins activate unique subsets of target genes under hypoxia. The mechanism...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3749168/ https://ncbi.nlm.nih.gov/pubmed/23991099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072358 |
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