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Enhanceosomes as integrators of hypoxia inducible factor (HIF) and other transcription factors in the hypoxic transcriptional response

Hypoxia is a prevalent attribute of the solid tumor microenvironment that promotes the expression of genes through posttranslational modifications and stabilization of alpha subunits (HIF1α and HIF2α) of hypoxia-inducible factors (HIFs). Despite significant similarities, HIF1 (HIF1α/ARNT) and HIF2 (...

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Detalhes bibliográficos
Main Authors: Pawlus, Matthew R., Hu, Cheng-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700616/
https://ncbi.nlm.nih.gov/pubmed/23707522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2013.05.018
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