[Val12] HRAS downregulates GLUT2 in beta cells of transgenic mice without affecting glucose homeostasis.

Glucose-induced insulin release from pancreatic beta cells depends on the beta-cell metabolism of glucose, which generates intracellular signals for secretion. The beta-cell glucose transporter isotype GLUT2 and the glucose phosphorylating enzyme glucokinase have both been implicated in coupling ins...

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Autores principales: Tal, M, Wu, Y J, Leiser, M, Surana, M, Lodish, H, Fleischer, N, Weir, G, Efrat, S
Formato: Artigo
Lenguaje:Inglês
Publicado: 1992
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC402094/
https://ncbi.nlm.nih.gov/pubmed/1631055
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