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[Val12] HRAS downregulates GLUT2 in beta cells of transgenic mice without affecting glucose homeostasis.
Glucose-induced insulin release from pancreatic beta cells depends on the beta-cell metabolism of glucose, which generates intracellular signals for secretion. The beta-cell glucose transporter isotype GLUT2 and the glucose phosphorylating enzyme glucokinase have both been implicated in coupling ins...
Tallennettuna:
| Julkaisussa: | Proc Natl Acad Sci U S A |
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| Päätekijät: | , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
1992
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC402094/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1631055/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.13.5744 |
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