Ribozyme mediated destruction of RNA in vivo.

Previous studies have demonstrated that high ribozyme to substrate ratios are required for ribozyme inhibitory function in nuclear extracts. To obtain high intracellular levels of ribozymes, tRNA genes, known to be highly expressed in most tissues, have been modified for use as ribozyme expression c...

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Detalles Bibliográficos

Publicado en:	EMBO J
Autores principales:	Cotten, M, Birnstiel, M L
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Publishing Group 1989
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC402074/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2684648/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb08564.x
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