Amyloidosis, Inflammation, and Oxidative Stress in the Heart of an Alkaptonuric Patient

Background. Alkaptonuria, a rare autosomal recessive metabolic disorder caused by deficiency in homogentisate 1,2-dioxygenase activity, leads to accumulation of oxidised homogentisic acid in cartilage and collagenous structures present in all organs and tissues, especially joints and heart, causing...

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Detaylı Bibliyografya
Asıl Yazarlar: Millucci, Lia, Ghezzi, Lorenzo, Paccagnini, Eugenio, Giorgetti, Giovanna, Viti, Cecilia, Braconi, Daniela, Laschi, Marcella, Geminiani, Michela, Soldani, Patrizia, Lupetti, Pietro, Orlandini, Maurizio, Benvenuti, Chiara, Perfetto, Federico, Spreafico, Adriano, Bernardini, Giulia, Santucci, Annalisa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi Publishing Corporation 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4020161/
https://ncbi.nlm.nih.gov/pubmed/24876668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/258471
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