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Amyloidosis, Inflammation, and Oxidative Stress in the Heart of an Alkaptonuric Patient
Background. Alkaptonuria, a rare autosomal recessive metabolic disorder caused by deficiency in homogentisate 1,2-dioxygenase activity, leads to accumulation of oxidised homogentisic acid in cartilage and collagenous structures present in all organs and tissues, especially joints and heart, causing...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4020161/ https://ncbi.nlm.nih.gov/pubmed/24876668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/258471 |
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