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Modulation of a voltage-gated Na(+) channel by sevoflurane involves multiple sites and distinct mechanisms
Halogenated inhaled general anesthetic agents modulate voltage-gated ion channels, but the underlying molecular mechanisms are not understood. Many general anesthetic agents regulate voltage-gated Na(+) (Na(V)) channels, including the commonly used drug sevoflurane. Here, we investigated the putativ...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4020080/ https://ncbi.nlm.nih.gov/pubmed/24753583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405768111 |
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