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Proteasomal interaction as a critical activity modulator of the human constitutive androstane receptor

The CAR (constitutive androstane receptor; NR1I3) is a critical xenobiotic sensor that regulates xenobiotic metabolism, drug clearance, energy and lipid homoeostasis, cell proliferation and development. Although constitutively active, in hepatocytes CAR is normally held quiescent through a tethering...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Chen, Tao, Laurenzana, Elizabeth M., Coslo, Denise M., Chen, Fengming, Omiecinski, Curtis J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019979/
https://ncbi.nlm.nih.gov/pubmed/24224465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20130685
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