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Presynaptic glycine receptors as a potential therapeutic target for hyperekplexia disease
While postsynaptic GlyRs as α/β heteromers attract the most research attention, little is known about the role of presynaptic GlyRs, likely α homomers, in diseases. Here, we demonstrate that DH-CBD, a nonpsychoactive cannabinoid, can rescue GlyR functional deficiency and exaggerated acoustic and tac...
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| Autors principals: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4019963/ https://ncbi.nlm.nih.gov/pubmed/24390226 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3615 |
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