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Folate receptor-targeted liposomes enhanced the antitumor potency of imatinib through the combination of active targeting and molecular targeting

PURPOSE: Imatinib inhibits platelet-derived growth factor receptor (PDGFR), and evidence shows that PDGFR participates in the development and progression of cervical cancer. Although imatinib has exhibited preclinical activity against cervical cancer, only minimal clinical therapeutic efficacy was o...

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Main Authors: Ye, Peng, Zhang, Wendian, Yang, Tan, Lu, Yao, Lu, Miao, Gai, Yongkang, Ma, Xiang, Xiang, Guangya
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019625/
https://ncbi.nlm.nih.gov/pubmed/24855354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S60178
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