Folate receptor-targeted liposomes enhanced the antitumor potency of imatinib through the combination of active targeting and molecular targeting

PURPOSE: Imatinib inhibits platelet-derived growth factor receptor (PDGFR), and evidence shows that PDGFR participates in the development and progression of cervical cancer. Although imatinib has exhibited preclinical activity against cervical cancer, only minimal clinical therapeutic efficacy was o...

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Bibliographic Details
Main Authors: Ye, Peng, Zhang, Wendian, Yang, Tan, Lu, Yao, Lu, Miao, Gai, Yongkang, Ma, Xiang, Xiang, Guangya
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2014
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019625/
https://ncbi.nlm.nih.gov/pubmed/24855354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S60178
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