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Synthesis and Evaluation of A Novel Ligand for Folate-mediated Targeting liposomes

Folate receptors (FRs) have been identified as cellular surface markers for cancer and leukemia. Liposomes containing lipophilic derivatives of folate have been shown to effectively target FR-expressing cells. Here, we report the synthesis of a novel lipophilic folate derivative, folate-polyethylene...

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Detalhes bibliográficos
Main Authors: Xiang, Guangya, Wu, Jun, Lu, Yanhui, Liu, Zhilan, Lee, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2424191/
https://ncbi.nlm.nih.gov/pubmed/18258394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2007.12.030
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