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Potent and Specific Inhibition of Glycosidases by Small Artificial Binding Proteins (Affitins)

Glycosidases are associated with various human diseases. The development of efficient and specific inhibitors may provide powerful tools to modulate their activity. However, achieving high selectivity is a major challenge given that glycosidases with different functions can have similar enzymatic me...

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Detalhes bibliográficos
Main Authors: Correa, Agustín, Pacheco, Sabino, Mechaly, Ariel E., Obal, Gonzalo, Béhar, Ghislaine, Mouratou, Barbara, Oppezzo, Pablo, Alzari, Pedro M., Pecorari, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019568/
https://ncbi.nlm.nih.gov/pubmed/24823716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097438
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