Mucosal Immunization with Integrase-Defective Lentiviral Vectors Protects against Influenza Virus Challenge in Mice

Recent reports highlight the potential for integrase-defective lentiviral vectors (IDLV) to be developed as vaccines due to their ability to elicit cell-mediated and humoral immune responses after intramuscular administration. Differently from their integrase-competent counterpart, whose utility for...

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Autors principals: Fontana, Judith M., Christos, Paul J., Michelini, Zuleika, Negri, Donatella, Cara, Andrea, Salvatore, Mirella
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019533/
https://ncbi.nlm.nih.gov/pubmed/24824623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097270
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