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Intranasal Administration of Integrase Defective Lentiviral Vectors Expressing mAbs Protects from H5 Influenza Virus Challenge In Vivo

BACKGROUND: Despite medical advances, we are often unable to rapidly protect non-immune populations from infectious agents. Passive immunotherapy is a fast method of protection, but large-scale administration of monoclonal antibodies (mAbs) in unpractical. The delivery of mAbs using a viral vector c...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Michelini, Zuleika, Fontana, Judith, Yang, Jianjun, Negri, Donatella, Cara, Andrea, Salvatore, Mirella
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7107124/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx163.1355
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