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BNIP3 Regulates AT101 [(-)-Gossypol] Induced Death in Malignant Peripheral Nerve Sheath Tumor Cells

Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive Schwann cell-derived sarcomas and are the leading cause of mortality in patients with neurofibromatosis type 1 (NF1). Current treatment modalities have been largely ineffective, resulting in a high rate of MPNST recurrence and poor fiv...

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Библиографические подробности
Главные авторы: Kaza, Niroop, Kohli, Latika, Graham, Christopher D., Klocke, Barbara J., Carroll, Steven L., Roth, Kevin A.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019476/
https://ncbi.nlm.nih.gov/pubmed/24824755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096733
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