Chymase inhibition prevents myocardial fibrosis through the attenuation of NOX4‐associated oxidative stress in diabetic hamsters

Aims/Introduction:  Diabetic cardiomyopathy entails the cardiac injury induced by diabetes, independent of vascular disease or hypertension. Despite numerous experimental studies and clinical trials, the pathogenesis of diabetic cardiomyopathy remains elusive. Here, we report that chymase, an immedi...

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Detalhes bibliográficos
Main Authors: Maeda, Yasutaka, Inoguchi, Toyoshi, Takei, Ryoko, Hendarto, Hari, Ide, Makoto, Inoue, Tomoaki, Kobayashi, Kunihisa, Urata, Hidenori, Nishiyama, Akira, Takayanagi, Ryoichi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019255/
https://ncbi.nlm.nih.gov/pubmed/24843590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.2040-1124.2012.00202.x
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