Reduced Expression of Adipose Triglyceride Lipase Enhances Tumor Necrosis Factor α-induced Intercellular Adhesion Molecule-1 Expression in Human Aortic Endothelial Cells via Protein Kinase C-dependent Activation of Nuclear Factor-κB

We examined the effects of adipose triglyceride lipase (ATGL) on the initiation of atherosclerosis. ATGL was recently identified as a rate-limiting triglyceride (TG) lipase. Mutations in the human ATGL gene are associated with neutral lipid storage disease with myopathy, a rare genetic disease chara...

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Detalhes bibliográficos
Main Authors: Inoue, Tomoaki, Kobayashi, Kunihisa, Inoguchi, Toyoshi, Sonoda, Noriyuki, Fujii, Masakazu, Maeda, Yasutaka, Fujimura, Yoshinori, Miura, Daisuke, Hirano, Ken-ichi, Takayanagi, Ryoichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173212/
https://ncbi.nlm.nih.gov/pubmed/21828047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.285650
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