Identification of a Group B Streptococcal Fibronectin Binding Protein, SfbA, That Contributes to Invasion of Brain Endothelium and Development of Meningitis

Group B Streptococcus (GBS) is currently the leading cause of neonatal meningitis. This is due to its ability to survive and multiply in the bloodstream and interact with specialized human brain microvascular endothelial cells (hBMEC), which constitute the blood-brain barrier (BBB). The exact mechan...

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Hlavní autoři: Mu, Rong, Kim, Brandon J., Paco, Czarinah, Del Rosario, Yvette, Courtney, Harry S., Doran, Kelly S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019170/
https://ncbi.nlm.nih.gov/pubmed/24643538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01559-13
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