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Binding of Glycoprotein Srr1 of Streptococcus agalactiae to Fibrinogen Promotes Attachment to Brain Endothelium and the Development of Meningitis

The serine-rich repeat glycoprotein Srr1 of Streptococcus agalactiae (GBS) is thought to be an important adhesin for the pathogenesis of meningitis. Although expression of Srr1 is associated with increased binding to human brain microvascular endothelial cells (hBMEC), the molecular basis for this i...

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Sonraí Bibleagrafaíochta
Main Authors: Seo, Ho Seong, Mu, Rong, Kim, Brandon J., Doran, Kelly S., Sullam, Paul M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464228/
https://ncbi.nlm.nih.gov/pubmed/23055927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002947
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