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Host MicroRNA Regulation of Human Cytomegalovirus Immediate Early Protein Translation Promotes Viral Latency

Reactivation of human cytomegalovirus (HCMV) is a significant cause of disease and death in immunocompromised patients, underscoring the need to understand how latency is controlled. Here we demonstrate that HCMV has evolved to utilize cellular microRNAs (miRNAs) in cells that promote latency to reg...

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Bibliografiske detaljer
Main Authors: O'Connor, Christine M., Vanicek, Jiri, Murphy, Eain A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4019081/
https://ncbi.nlm.nih.gov/pubmed/24599990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00481-14
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