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Tailoring chimeric ligands for studying and biasing ErbB receptor family interactions
We describe the development and application of a versatile semisynthetic strategy, based on a combination of sortase-mediated coupling and tetrazine ligation chemistry, which can be exploited for the efficient incorporation of tunable functionality into chimeric recombinant proteins. To demonstrate...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018821/ https://ncbi.nlm.nih.gov/pubmed/24481645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201307869 |
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