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Tailoring chimeric ligands for studying and biasing ErbB receptor family interactions

We describe the development and application of a versatile semisynthetic strategy, based on a combination of sortase-mediated coupling and tetrazine ligation chemistry, which can be exploited for the efficient incorporation of tunable functionality into chimeric recombinant proteins. To demonstrate...

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Bibliografische gegevens
Hoofdauteurs: Krueger, Andrew T., Kroll, Carsten, Sanchez, Edgar, Griffith, Linda G., Imperiali, Barbara
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018821/
https://ncbi.nlm.nih.gov/pubmed/24481645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201307869
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