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CLASS D β-LACTAMASES: A RE-APPRAISAL AFTER FIVE DECADES
Despite 70 years of clinical use, β-lactam antibiotics still remain at the forefront of antimicrobial chemotherapy. The major challenge to these life-saving therapeutics is the presence of bacterial enzymes (i.e., β-lactamases) that can hydrolyze the β-lactam bond and inactivate the antibiotic. Thes...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018812/ https://ncbi.nlm.nih.gov/pubmed/23902256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ar300327a |
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