The p53-induced factor Ei24 inhibits nuclear import through an importin β–binding–like domain

The etoposide-induced protein Ei24 was initially identified as a p53-responsive, proapoptotic factor, but no clear function has been described. Here, we use a nonbiased proteomics approach to identify members of the importin (IMP) family of nuclear transporters as interactors of Ei24 and characteriz...

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Main Authors: Lieu, Kim G., Shim, Eun-Hee, Wang, Jinling, Lokareddy, Ravi K., Tao, Tao, Cingolani, Gino, Zambetti, Gerard P., Jans, David A.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2014
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018778/
https://ncbi.nlm.nih.gov/pubmed/24821838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201304055
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