Protection against oxidative DNA damage and stress in human prostate by glutathione S-transferase P1

The pi-class glutathione S-transferase (GSTP1) actively protect cells from carcinogens and electrophilic compounds. Loss of GSTP1 expression via promoter hypermethylation is the most common epigenetic alteration observed in human prostate cancer. Silencing of GSTP1 can increase generation of reactiv...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kanwal, Rajnee, Pandey, Mitali, Bhaskaran, Natarajan, MacLennan, Gregory T, Fu, Pingfu, Ponsky, Lee E, Gupta, Sanjay
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018746/
https://ncbi.nlm.nih.gov/pubmed/22833520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.21939
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