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Protection against oxidative DNA damage and stress in human prostate by glutathione S-transferase P1
The pi-class glutathione S-transferase (GSTP1) actively protect cells from carcinogens and electrophilic compounds. Loss of GSTP1 expression via promoter hypermethylation is the most common epigenetic alteration observed in human prostate cancer. Silencing of GSTP1 can increase generation of reactiv...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018746/ https://ncbi.nlm.nih.gov/pubmed/22833520 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.21939 |
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