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Systematic evaluation of spliced alignment programs for RNA-seq data

High-throughput RNA sequencing is an increasingly accessible method for studying gene structure and activity on a genome-wide scale. A critical step in RNA-seq data analysis is the alignment of partial transcript reads to a reference genome sequence. To assess the performance of current mapping soft...

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Detalhes bibliográficos
Main Authors: Engström, Pär G, Steijger, Tamara, Sipos, Botond, Grant, Gregory R, Kahles, André, Rätsch, Gunnar, Goldman, Nick, Hubbard, Tim J, Harrow, Jennifer, Guigó, Roderic, Bertone, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018468/
https://ncbi.nlm.nih.gov/pubmed/24185836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2722
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