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Mannitol Bis-phosphate Based Inhibitors of Fructose 1,6-Bisphosphate Aldolases
[Image: see text] Several 5-O-alkyl- and 5-C-alkyl-mannitol bis-phosphates were synthesized and comparatively assayed as inhibitors of fructose bis-phosphate aldolases (Fbas) from rabbit muscle (taken as surrogate model of the human enzyme) and from Trypanosoma brucei. A limited selectivity was foun...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical Society
2011
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018070/ https://ncbi.nlm.nih.gov/pubmed/24900268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200129s |
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