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Highly Selective Inhibitors of Class II Microbial Fructose Bis-phosphate Aldolases

[Image: see text] We hereby describe the rationale synthesis and biochemical evaluation of the most powerful and selective inhibitors of class II fructose bis-phosphate aldolases so far reported. These inhibitors are of potential therapeutic interest, since the class II enzyme is present exclusively...

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Autors principals: Daher, Racha, Therisod, Michel
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2010
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007796/
https://ncbi.nlm.nih.gov/pubmed/24900183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100017c
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