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Thermodynamics of Ligand Binding and Efficiency
[Image: see text] Analysis of the experimental binding thermodynamics for approximately 100 protein−ligand complexes provides important insights into the factors governing ligand affinity and efficiency. The commonly accepted correlation between enthalpy and −TΔS is clearly observed for this relativ...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical Society
2011
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4018058/ https://ncbi.nlm.nih.gov/pubmed/24900326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200010k |
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