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Thermodynamics of Ligand Binding and Efficiency

[Image: see text] Analysis of the experimental binding thermodynamics for approximately 100 protein−ligand complexes provides important insights into the factors governing ligand affinity and efficiency. The commonly accepted correlation between enthalpy and −TΔS is clearly observed for this relativ...

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Autori principali: Reynolds, Charles H., Holloway, M. Katharine
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2011
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018058/
https://ncbi.nlm.nih.gov/pubmed/24900326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200010k
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