Novel Synthesis and Biological Evaluation of Enigmols as Therapeutic Agents for Treating Prostate Cancer

[Image: see text] Enigmol is a synthetic, orally active 1-deoxysphingoid base analogue that has demonstrated promising activity against prostate cancer. In these studies, the pharmacologic roles of stereochemistry and N-methylation in the structure of enigmols were examined. A novel enantioselective...

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Bibliografiset tiedot
Päätekijät: Garnier-Amblard, Ethel C., Mays, Suzanne G., Arrendale, Richard F., Baillie, Mark T., Bushnev, Anatoliy S., Culver, Deborah G., Evers, Taylor J., Holt, Jason J., Howard, Randy B., Liebeskind, Lanny S., Menaldino, David S., Natchus, Michael G., Petros, John A., Ramaraju, Harsha, Reddy, G. Prabhakar, Liotta, Dennis C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2011
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017995/
https://ncbi.nlm.nih.gov/pubmed/24900327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml2000164
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