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Organometallic Enantiomeric Scaffolding. A Strategy for the Enantiocontrolled Construction of Regio- and Stereodivergent Trisubstituted Piperidines from a Common Precursor

Reported herein is a general and efficient method to construct 2,3,6-trisubstituted piperidines in a substituent-independent fashion. From the high enantiopurity organometallic scaffold (−)-Tp(CO)(2)[(η-2,3,4)-(1S, 2S)-1-benzyloxycarbonyl-5-oxo-5,6-dihydro-2H-pyridin-2-yl)molybdenum (Tp = hydridotri...

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Detalhes bibliográficos
Main Authors: Wong, Heilam, Garnier-Amblard, Ethel C., Liebeskind, Lanny S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107969/
https://ncbi.nlm.nih.gov/pubmed/21513336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja201012p
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