Enigmol: A novel sphingolipid analog with anti-cancer activity against cancer cell lines and in vivo models for intestinal and prostate cancer

Sphingoid bases are cytotoxic for many cancer cell lines, and are thought to contribute to suppression of intestinal tumorigenesis in vivo by ingested sphingolipids. This study explored the behavior of a sphingoid base analog, (2S,3S,5S)-2-amino-3,5-dihydroxyoctadecane (“Enigmol”), that cannot be ph...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Symolon, Holly, Bushnev, Anatoliy, Peng, Qiong, Ramaraju, Harsha, Mays, Suzanne G., Allegood, Jeremy C., Pruett, Sarah T., Sullards, M. Cameron, Dillehay, Dirck L., Liotta, Dennis C., Merrill, Alfred H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536251/
https://ncbi.nlm.nih.gov/pubmed/21398423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0754
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