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Homology Model and Docking-Based Virtual Screening for Ligands of the σ(1) Receptor

[Image: see text] This study presents for the first time the 3D model of the σ(1) receptor protein as obtained from homology modeling techniques, shows the applicability of this structure to docking-based virtual screening, defines a computational strategy to optimize the results based on a combinat...

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Detalhes bibliográficos
Main Authors: Laurini, Erik, Col, Valentina Dal, Mamolo, Maria Grazia, Zampieri, Daniele, Posocco, Paola, Fermeglia, Maurizio, Vio, Luciano, Pricl, Sabrina
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2011
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017991/
https://ncbi.nlm.nih.gov/pubmed/24900272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml2001505
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