Загрузка...
Identification of Potent and Selective Glucosylceramide Synthase Inhibitors from a Library of N-Alkylated Iminosugars
[Image: see text] Glucosylceramide synthase (GCS) is an important target for clinical drug development for the treatment of lysosomal storage disorders and a promising target for combating type 2 diabetes. Iminosugars are useful leads for the development of GCS inhibitors; however, the effective imi...
Сохранить в:
| Главные авторы: | , , , , , , , , , , , , , , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Chemical Society
2010
|
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4017989/ https://ncbi.nlm.nih.gov/pubmed/24900289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100192b |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|