Discovery of a Potent Nicotinic Acid Receptor Agonist for the Treatment of Dyslipidemia

[Image: see text] Nicotinic acid has been used clinically for decades to control serum lipoproteins. Nicotinic acid lowers very low-density lipoprotein (VLDL)-cholesterol, low-density lipoprotein (LDL)-cholesterol, and lipoprotein-a (LPa), and it is also effective in raising high-density lipoprotein...

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Hauptverfasser: Qin, Jun, Rao, Ashwin, Chen, Xiao, Zhu, Xiaohong, Liu, Zhidan, Huang, Xianhai, Degrado, Sylvia, Huang, Ying, Xiao, Dong, Aslanian, Robert, Cheewatrakoolpong, Boonlert, Zhang, Hongtao, Greenfeder, Scott, Farley, Constance, Cook, John, Kurowski, Stan, Li, Qiu, van Heek, Margaret, Chintala, Madhu, Wang, Ganfeng, Hsieh, Yunsheng, Li, Fangbiao, Palani, Anandan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2010
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017979/
https://ncbi.nlm.nih.gov/pubmed/24900295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100251u
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