Design and Synthesis of Isoquinolidinobenzodiazepine Dimers, a Novel Class of Antibody–Drug Conjugate Payload

par Smith, Sean W., Jammalamadaka, Vasu, Borkin, Dmitry, Zhu, Jianyu, Degrado, Sylvia J., Lu, Jennifer, Huang, Jianqing, Jiang, Ying-Ping, Jain, Nareshkumar, Junutula, Jagath R.
Publié dans ACS Med Chem Lett (2017)

Discovery of a Potent Thiadiazole Class of Histamine H(3) Receptor Antagonist for the Treatment of Diabetes

par Rao, Ashwin U., Shao, Ning, Aslanian, Robert G., Chan, Tin-Yau, Degrado, Sylvia J., Wang, Li, McKittrick, Brian, Senior, Mary, West, Robert E., Williams, Shirley M., Wu, Ren-Long, Hwa, Joyce, Patel, Bhuneshwari, Zheng, Shuqin, Sondey, Christopher, Palani, Anandan
Publié 2011

Discovery of a Potent Nicotinic Acid Receptor Agonist for the Treatment of Dyslipidemia

par Qin, Jun, Rao, Ashwin, Chen, Xiao, Zhu, Xiaohong, Liu, Zhidan, Huang, Xianhai, Degrado, Sylvia, Huang, Ying, Xiao, Dong, Aslanian, Robert, Cheewatrakoolpong, Boonlert, Zhang, Hongtao, Greenfeder, Scott, Farley, Constance, Cook, John, Kurowski, Stan, Li, Qiu, van Heek, Margaret, Chintala, Madhu, Wang, Ganfeng, Hsieh, Yunsheng, Li, Fangbiao, Palani, Anandan
Publié 2010

Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3 Positive Tumor Cells and Tumor Vasculature

par Seaman, Steven, Zhu, Zhongyu, Saha, Saurabh, Zhang, Xiaoyan M., Yang, Mi Young, Hilton, Mary Beth, Morris, Karen, Szot, Christopher, Morris, Holly, Swing, Deborah A., Tessarollo, Lino, Smith, Sean W., Degrado, Sylvia, Borkin, Dmitry, Jain, Nareshkumar, Scheiermann, Julia, Feng, Yang, Wang, Yanping, Li, Jinyu, Welsch, Dean, DeCrescenzo, Gary, Chaudhary, Amit, Zudaire, Enrique, Klarmann, Kimberly D., Keller, Jonathan R., Dimitrov, Dimiter S, St Croix, Brad
Publié dans Cancer Cell (2017)

Discovery of SCH 900271, a Potent Nicotinic Acid Receptor Agonist for the Treatment of Dyslipidemia

par Palani, Anandan, Rao, Ashwin U., Chen, Xiao, Huang, Xianhai, Su, Jing, Tang, Haiqun, Huang, Ying, Qin, Jun, Xiao, Dong, Degrado, Sylvia, Sofolarides, Michael, Zhu, Xiaohong, Liu, Zhidan, McKittrick, Brian, Zhou, Wei, Aslanian, Robert, Greenlee, William J., Senior, Mary, Cheewatrakoolpong, Boonlert, Zhang, Hongtao, Farley, Constance, Cook, John, Kurowski, Stan, Li, Qiu, van Heek, Margaret, Wang, Gangfeng, Hsieh, Yunsheng, Li, Fangbiao, Greenfeder, Scott, Chintala, Madhu
Publié 2011