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The E3 Ligase CHIP: Insights into Its Structure and Regulation
The carboxy-terminus of Hsc70 interacting protein (CHIP) is a cochaperone E3 ligase containing three tandem repeats of tetratricopeptide (TPR) motifs and a C-terminal U-box domain separated by a charged coiled-coil region. CHIP is known to function as a central quality control E3 ligase and regulate...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Hindawi Publishing Corporation
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4017836/ https://ncbi.nlm.nih.gov/pubmed/24868554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/918183 |
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