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Temporal dynamics and developmental memory of 3D chromatin architecture at Hox gene loci

Hox genes are essential regulators of embryonic development. Their step-wise transcriptional activation follows their genomic topology and the various states of activation are subsequently memorized into domains of progressively overlapping gene products. We have analyzed the 3D chromatin organizati...

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Autori principali: Noordermeer, Daan, Leleu, Marion, Schorderet, Patrick, Joye, Elisabeth, Chabaud, Fabienne, Duboule, Denis
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017647/
https://ncbi.nlm.nih.gov/pubmed/24843030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02557
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