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Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation
The molecular mechanisms that govern thymocyte development and maturation are incompletely understood. The P21-activated kinase 2 (Pak2) is an effector for the Rho family GTPases Rac and Cdc42 that regulate actin cytoskeletal remodeling, but its role in the immune system remains poorly understood. I...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4017645/ https://ncbi.nlm.nih.gov/pubmed/24843022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02270 |
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