Clinical implications of BRAF mutation test in colorectal cancer

Knowledge about the clinical significance of V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) mutations in colorectal cancer (CRC) is growing. BRAF encodes a protein kinase involved with intracellular signaling and cell division. The gene product is a downstream effector of Kirsten Ras 1(KRAS)...

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Bibliographic Details
Main Authors: Mojarad, Ehsan Nazemalhosseini, Farahani, Roya Kishani, Haghighi, Mahdi Montazer, Aghdaei, Hamid Asadzadeh, Kuppen, Peter JK, Zali, Mohammad Reza
Format: Artigo
Language:Inglês
Published: Research Institute for Gastroenterology and Liver Diseases 2013
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017487/
https://ncbi.nlm.nih.gov/pubmed/24834238
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