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Applications of alignment-free methods in epigenomics

Epigenetic mechanisms play an important role in the regulation of cell type-specific gene activities, yet how epigenetic patterns are established and maintained remains poorly understood. Recent studies have supported a role of DNA sequences in recruitment of epigenetic regulators. Alignment-free me...

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Detalhes bibliográficos
Main Authors: Pinello, Luca, Lo Bosco, Giosuè, Yuan, Guo-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017331/
https://ncbi.nlm.nih.gov/pubmed/24197932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbt078
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